Description
InsulinPorcineisatwochain,glycosylatedpolypeptidechaincontaining51 aminoacidsandhavingamolecularmassof5733 Dalton.Theαandβchainsarejoinedbytwointerchaindisulfidebonds.Theαchaincontainsanintrachaindisulfidebond.Insulinregulatesthecellularuptake,utilization,andstorageofglucose,aminoacids,andfattyacidsandinhibitsthebreakdownofglycogen,protein,andfat.InsulinPorcineispurifiedbyproprietarychromatographictechniques
Source
PorcinePancreas
Purity
Greaterthan98.0%asdeterminedby:(a)AnalysisbyRP-HPLC.(b)AnalysisbySDS-PAGE.
BIOLOGicalActivity
26 units/mg.
Formulation
TheInsulinPorcinewaslyophilizedfromaconcentrated(1mg/ml)solutionwithnoadditives.
Shipping
Atambienttemperature.Uponreceipt,storetheproductatthetemperaturerecommended below.
Storage/Expiration
LyophilizedInsulinPorcinealthoughstableatroomtemperaturefor3 weeks,shouldbestoreddesiccatedbelow –18°C.UponreconstitutionInsulinPorcineshouldbestoredat4°Cbetween2–7daysandforfutureusebelow –18°C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.
PhysicalAppearance
Sterilefilteredwhitelyophilized(freeze-dried)powder.
