Biovendor/ICAM-1 Human Chinese Hamster Ovary Cells (CHO)/RBG10180100/100 μg-免疫在线蚂蚁淘旗下平台

商品详细Biovendor/ICAM-1 Human Chinese Hamster Ovary Cells (CHO)/RBG10180100/100 μg

Biovendor/ICAM-1 Human Chinese Hamster Ovary Cells (CHO)/RBG10180100/100 μg

商品编号： RBG10180100

品牌： Biovendor-Laboratorni

市场价： ¥0.00

美元价： 0.00

产地：美国(厂家直采)

公司：

产品分类：细胞因子

公司分类： cytokine

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Regulatorystatus:RUO
Type:Recombinant
Source:ChineseHamsterOvaryCells(CHO)
Othernames:Intercellularadhesionmolecule1,Majorgrouprhinovirusreceptor,CD54antigen,SurfaceantigenofactivatedBcells
Species:Human

Type

Recombinant

Description

ICAMsaremembersoftheIgsuperfamilyofcalcium-independenttransmembraneglycoproteins.ICAM-1 isaligandforthelymphocytefunction-associatedantigen(LFA)andMac-1 integrins,aswellasthemajorhumanrhinovirusreceptor.TheprimaryfunctionofICAM-1 istoprovideadhesionbetweenendothelialcellsandleukocytesafterstressorinjury.ThehumanICAM-1 genecodesfora505 aminoacidtransmembraneglycoproteincontaininga29 aminoacidcytoplasmicdomain,a23 aminoacidtransmembranedomain,anda453 aminoacidextracellulardomain.RecombinantHumanICAM-1 isa49.5 kDaglycoproteincomprisingtheextracellulardomain(453 aminoacidresidues)ofICAM-1. MonomericglycosylatedICAM-1 migratesatanapparentmolecularweightofapproximately72.0–80.0 kDabySDS-PAGEanalysisunderreducingconditions.

AminoAcidSequence

QTSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYE

Source

ChineseHamsterOvaryCells(CHO)

Purity

98%

BIOLOGicalActivity

ICAM-1 supportedtheadhesionofmorethan50%PMA-stimulatedHSB2cellstoplatescoatedat25 µg/mlICAM-1 concentration.

Endotoxin

Endotoxinlevelis<0.1 ng/μgofprotein(<1EU/μg).

Reconstitution

Centrifugethevialpriortoopening.Reconstituteinwatertoaconcentrationof0.1–1.0 mg/ml.Donotvortex.Forextendedstorage,itisrecommendedtofurtherdiluteinabuffercontainingacarrierprotein(example0.1%BSA)andstoreinworkingaliquotsat-20°Cto –80°C.

Storage/Expiration

–20°C

品牌介绍

miREIA是一种基于免疫测定的新型miRNA定量方法，涉及从患者样品中分离出的miRNA与互补的生物素化DNA寡核苷酸探针杂交。然后通过固定有完美匹配的DNA / miRNA杂交体的微量滴定板固定的单克隆抗体捕获DNA / RNA杂交体。下一步是复制标准ELISA方案。该测定可在常规免疫测定设备上运行，与标准临床工作流程兼容，不需要扩增步骤，并且包括miRNA分析在内的结果可在不到三个小时的时间内获得。