Biovendor/GDF-15/MIC-1 Human Cell Culture/RBG10164100/100 μg-免疫在线蚂蚁淘旗下平台

商品详细Biovendor/GDF-15/MIC-1 Human Cell Culture/RBG10164100/100 μg

Biovendor/GDF-15/MIC-1 Human Cell Culture/RBG10164100/100 μg

商品编号： RBG10164100

品牌： Biovendor-Laboratorni

市场价： ¥18000.00

美元价： 10800.00

产地：美国(厂家直采)

公司：

产品分类：细胞因子

公司分类： cytokine

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Regulatorystatus:RUO
Type:Recombinant
Source:CellCulture
Othernames:Growthdifferentiationfactor15
Species:Human

Type

Recombinant

Description

GDF-15 belongstotheTGF-βcytokinefamily,whosemembersplayanimportantroleduringprenataldevelopmentandpostnatalgrowth,andtheremodelingandmaintenanceofavarietyoftissuesandorgans.GDF-15 isexpressedpredominantlyintheplacentaand,toamuchlesserextent,invariousothertissues.ThepresenceofGDF-15 inamnioticfluidanditselevatedlevelsintheseraofpregnantwomensuggestGDF-15"s involvementingestationandembryonicdevelopment.GDF-15 generallyexertstumorsuppressiveactivitiesandisoneofthepredominantfactorsproducedandsecretedinresponsetoactivationofthep53pathway.Interestingly,theserumlevelofGDF-15 ispositivelycorrelatedwithneoplasticprogressionofseveraltumortypes,includingcertaincolorectal,pancreatic,andprostatecancers.HumanGDF-15/MIC-1 isadisulfidelinkedhomodimericproteinconsistingoftwo112 aminoacidpolypeptidechains.ThecalculatedmolecularweightofHumanGDF-15/MIC-1 is24.6 kDa.

AminoAcidSequence

ARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCI

Source

CellCulture

Purity

98%

BIOLOGicalActivity

DeterminedbyitsABIlitytoinhibitalkalinephosphataseactivityindifferentiatingMC3T3/E1osetoblastcells.TheexpectedED₅₀forthiseffectis1.0–3.0 μg/ml.

Storage/Expiration

–20°C

品牌介绍

miREIA是一种基于免疫测定的新型miRNA定量方法，涉及从患者样品中分离出的miRNA与互补的生物素化DNA寡核苷酸探针杂交。然后通过固定有完美匹配的DNA / miRNA杂交体的微量滴定板固定的单克隆抗体捕获DNA / RNA杂交体。下一步是复制标准ELISA方案。该测定可在常规免疫测定设备上运行，与标准临床工作流程兼容，不需要扩增步骤，并且包括miRNA分析在内的结果可在不到三个小时的时间内获得。