Biovendor/Activin A Human Rat Murine E. coli (E.coli-derived)/RBG10052E100/100 μg-免疫在线蚂蚁淘旗下平台

商品详细Biovendor/Activin A Human Rat Murine E. coli (E.coli-derived)/RBG10052E100/100 μg

Biovendor/Activin A Human Rat Murine E. coli (E.coli-derived)/RBG10052E100/100 μg

商品编号： RBG10052E100

品牌： Biovendor-Laboratorni

市场价： ¥20800.00

美元价： 12480.00

产地：美国(厂家直采)

公司：

产品分类：细胞因子

公司分类： cytokine

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Regulatorystatus:RUO
Type:Recombinant
Source:E.coli
Othernames:Inhibinbeta-1,FRP,FSH(Follicle-stimulatinghormone)-releasingprotein
Species:Human,Murine,Rat

Type

Recombinant

Description

ActivinA isaTGF-βfamilymemberthatexhibitsawiderangeofBIOLOGicalactivities,includingregulationofcellularproliferationanddifferentiation,andpromotionofneuronalsurvival.ElevatedlevelsofActivinA inhumancolorectaltumorsandinpostmenopausalwomenhavebeenimplicatedincolorectalandbreastcancers,respectively.ThebiologicalactivitiesofActivinA canbeneutralizedbyinhibinsandbythediffusIBLeTGF-βantagoNIST,follistatin.ActivinA bindstothetwoformsofactivinreceptortypeI(ActRI-A andActRI-B)andtwoformsofactivinreceptortypeII(ActRII-A andActRII-B).Activinsarehomodimersorheterodimersofdifferentβsubunits.TheyareproducedasprecursorproteinswithanaminoterminalpropeptidethatiscleavedtoreleasetheC-terminalbioactiveligand.Human/Murine/RatActivinA isa26.0 kDadisulfide-linkedhomodimeroftwoβAchains,eachcontaining116 aminoacidresidues.

AminoAcidSequence

GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS

Source

E.coli

Purity

97

BiologicalActivity

TheED50asdeterminedbyitsABIlitytoinhibittheproliferationofmurineMPC-11 cellsis2.0 ng/ml,correspondingtoaspecificactivityof5×10⁵ units/mg.

Storage/Expiration

–20°C

品牌介绍

miREIA是一种基于免疫测定的新型miRNA定量方法，涉及从患者样品中分离出的miRNA与互补的生物素化DNA寡核苷酸探针杂交。然后通过固定有完美匹配的DNA / miRNA杂交体的微量滴定板固定的单克隆抗体捕获DNA / RNA杂交体。下一步是复制标准ELISA方案。该测定可在常规免疫测定设备上运行，与标准临床工作流程兼容，不需要扩增步骤，并且包括miRNA分析在内的结果可在不到三个小时的时间内获得。